A toy shop and two clothing stores in Stamford will close within the next few weeks as the town centre continues to change.
High Street stores Dorothy Perkins and Burton will shut on Saturday, July 6.
The shops are both owned by Arcadia, which declined to comment on the news.
But a source said it was hoped the 10 staff affected by the closures will be relocated to other branches.
Stamford Models and Toys has been trading in Maiden Lane for the last five years but it will close for the final time next weekend.
Owners Richard Peel and Dean Barlow say it has been a tough decision but after experiencing a 50 per cent drop in sales since Christmas, they were left with no choice.
Mr Peel said: “Trade had been great until about six months ago. I think the recession has had a big impact.
“People come in to look around but they just don’t buy anything because they don’t have the money to spare.”
The shop is hosting a sale until its final day of trading on Saturday, June 29.
Mr Peel said: “We would like to thank all our customers for their support over the last five years.
“We came into the town as outsiders but everyone has been friendly and we have made a lot of friends who we will miss.
“We have enjoyed trading in the town and would encourage everyone to support their local businesses to stop any more of them having to close.”
The YMCA charity shop in St Paul’s Street has also closed.
But it is not all doom and gloom in the town centre. A new Thai restaurant, Buddah Lounge, has opened in St Mary’s Hill.
The White Company opened its doors in High Street last month, while men’s gift shop Digby & Gunn has opened in Cheyne Lane.
Stamford Chamber of Trade and Commerce president Tim Lee said he was confident the empty shops would soon fill up.
He also said Stamford Town Team was trying to get permission for art students to go in to vacant shops and come up with temporary pieces to paint on the empty windows.