East Midlands Ambulance Service NHS Trust is urging people to start 2013 safe and well.
The traditional party night marks the end of more than a fortnight of seasonal celebrations which puts more demand on ambulances than any other time of the year.
On the last Friday before Christmas, December 21, the service dealt with 2,384 emergency calls - 457 more than would normally be received on a typical Friday.
The service is preparing for a spike in emergency calls tonight (Monday).
Ambulance service operations director Pete Ripley said: “Christmas and New Year’s Eve celebrations always mean an increase in calls.
“Alcohol makes people take risks and that can lead to anything from a fall resulting in a head injury to not being able to make your way home.
“We have to deal with too many people who are so intoxicated they’re lying on the pavement alone and that’s a very vulnerable situation.
“If you’re planning on celebrating the new year also make a plan to stay safe and well that includes staying hydrated, knowing your alcohol limits and ensuring you can get home at the end of the night.”
People are being urged to stay safe by keeping warm; eat something before you start drinking alcohol; ensure you have soft drinks or water to avoid dehydration; plan your journey home and ensure you save money for a taxi or bus and look out for your friends and don’t let anyone get left behind.