THE family of 15-month-old Lana Leeson, who has battled the odds against a rare blood disorder, could face the heartbreaking prospect of a new donor search.
The brave tot, who suffers from hemophagocytic lymphohistiocytosis, has shown signs of rejecting a life-saving bone marrow transplant.
Last year Lana, pictured above with mum Vanessa, defied doctors when, braced for a six-month stay, she showed fighting spirit to be out for Christmas after a successful transplant operation.
Donated cells have grown over time to make new blood cells. But recent engraftment results analysing the cell growth show a reduction from 100 per cent to 68 per cent in April, down to 38 per cent this month.
If the drop continues doc-tors will need to see if the original donor, a 39-year-old woman from Germany, can donate more cells. If not, the Leeson family, of New Road in Oundle, will need a new donor.
Vanessa, 28, said: "This was a complete shock for us as she looked so well. The doctors have changed her medication slightly and it is hoped it will help bring back or at least stabilise her engraftment but we will have to wait and see."